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Alexis De Haven Brandon Selected Research

PI 620

7/2009Biological properties of potent inhibitors of class I phosphatidylinositide 3-kinases: from PI-103 through PI-540, PI-620 to the oral agent GDC-0941.

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Alexis De Haven Brandon Research Topics

Disease

10Neoplasms (Cancer)
11/2020 - 07/2009
3Colorectal Neoplasms (Colorectal Cancer)
07/2019 - 08/2013
1Neuroblastoma
11/2020
1Multiple Myeloma
03/2020
1Carcinoma (Carcinomatosis)
01/2020
1Ovarian Neoplasms (Ovarian Cancer)
01/2020
1Melanoma (Melanoma, Malignant)
01/2019
1Carcinogenesis
12/2016
1Rhabdomyosarcoma
11/2013
1Glioblastoma (Glioblastoma Multiforme)
07/2009

Drug/Important Bio-Agent (IBA)

4Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
03/2020 - 11/2013
3Phosphotransferases (Kinase)IBA
01/2019 - 12/2016
2trametinibIBA
03/2020 - 01/2019
2InterferonsIBA
07/2019 - 01/2019
2PI103IBA
08/2013 - 07/2009
1Temozolomide (Temodar)FDA LinkGeneric
11/2020
1CYC065IBA
11/2020
1Adrenergic Agents (Adrenergic Drugs)IBA
11/2020
1Transcription Factors (Transcription Factor)IBA
11/2020
1Dexamethasone (Maxidex)FDA LinkGeneric
03/2020
1Glucocorticoid Receptors (Glucocorticoid Receptor)IBA
03/2020
1Estrogens (Estrogen)FDA Link
01/2020
1Cyclin-Dependent Kinases (cdk Proteins)IBA
01/2019
1BOS172722IBA
01/2018
1Biomarkers (Surrogate Marker)IBA
01/2016
1Small Interfering RNA (siRNA)IBA
11/2013
1AZD 6244IBA
11/2013
1Mitogen-Activated Protein KinasesIBA
11/2013
1Phosphatidylinositols (Phosphatidylinositol)IBA
11/2013
1(5- (2,4- bis((3S)- 3- methylmorpholin- 4- yl)pyrido(2,3- d)pyrimidin- 7- yl)- 2- methoxyphenyl)methanolIBA
11/2013
1Mechanistic Target of Rapamycin Complex 1IBA
11/2013
1tanespimycin (17AAG)IBA
08/2013
1Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA
08/2013
1LigandsIBA
08/2013
1Antineoplastic Agents (Antineoplastics)IBA
01/2010
1Drug CombinationsIBA
01/2010
1Etoposide (VP 16)FDA LinkGeneric
01/2010
1GemcitabineFDA Link
01/2010
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
01/2010
1PI 620IBA
07/2009
1Protein Isoforms (Isoforms)IBA
07/2009
1PI 540IBA
07/2009
12- (1H- indazol- 4- yl)- 6- (4- methanesulfonylpiperazin- 1- ylmethyl)- 4- morpholin- 4- ylthieno(3,2- d)pyrimidineIBA
07/2009

Therapy/Procedure

2Therapeutics
11/2020 - 01/2020
1Injections
01/2020
1Drug Therapy (Chemotherapy)
01/2010